Spondylosis is spinal degeneration and deformity of the joint(s) of two or more vertebrae that commonly occurs with aging. Often there is herniation of the nucleus pulposus of one or more intervertebral discs and/or formation of osteophytes.

When the space between two adjacent vertebrae narrows, compression of a nerve root emerging from the spinal cord may result in radiculopathy (sensory system and motor system disturbances, such as severe pain in the neck, shoulder, arm, back, and/or leg, accompanied by muscular weakness). Less commonly, direct pressure on the spinal cord (typically in the cervical spine) may result in global weakness, gait dysfunction, loss of balance, and loss of bowel and/or bladder control. The patient may experience a phenomenon of shocks in hands and legs because of nerves contraction and lack of blood flow. If vertebrae of the neck are involved it is labeled Cervical Spondylosis. Lower back spondylosis is labeled Lumbar Spondylosis.

In simple terms, spondylolisthesis describes the displacement of a vertrebra or the vertebral column in relation to the vertebrae below. It was first described in 1782 by a Belgian obstetrician, Dr. Herbinaux. He reported a bony prominence anterior to the sacrum that obstructed the vagina of a small number of patients.

The term "spondylolisthesis" was coined in 1854, from the Greek "spondylo" for vertebrae and "olisthesis" for slip. These "slips" occur most commonly in the lumbar spine.

A hangman's fracture is a specific type of spondylolisthesis where the C1 vertebra is displaced anteriorly relative to the C2 vertebra due to fractures of the C2 vertebra's pedicles.

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